TAGS: OMICs; bacterial endotoxin; chicken;
The aim of the project is to determine the change in the proteome and metabolome of chicken following endotoxin challenge and the effect of diet on this response.
Description of the project
The Early Stage Researcher (ESR) will determine the effects of natural immunomodulatory compounds as supplements to the diet of chicken and the potential protection provided to challenge by bacterial endotoxin. Samples from control and challenged chicken will be analysed using OMICs (metabolomics, microbiomics, proteomics and transcriptomics) technologies. The ESR will subsequently identify candidate molecules for further investigation by developing appropriate assay systems. The ESR will evaluate growth performance of healthy and challenged chicken, define the protocol to use for proteomics and metabolomics for integrated tissue analysis in chicken, define the intestinal microbiome, demonstrate the effects of immunomodulatory molecules on proteins expressed in the microbiota, intestine, serum and muscle following challenge and finally identify biomarkers of nutritional status and for digestion of feed in chickens.
The ESR will be enrolled in the University of Glasgow (https://www.gla.ac.uk/) under the supervision of Prof Maureen Bain and will be awarded a Double Doctorate degree in co-tutelle with the University of Zagreb (http://www.unizg.hr/homepage/), under the supervision of Prof Vladimir Mrljak. The supervision team is completed by a non academic supervisor, Dr Geert Bruggeman, of Nutrition Science (http://www.nutrition-sciences.com/), Belgium.
The selected candidate will participate in the network’s training activities and work placements in the laboratories of the participating academic and industrial partners.
Eligibility criteria are indicated at admission rules page
For the specific ESR 3 position, it will be considered advantageous if the candidate has:
- practical experience of animal handling
- knowledge and experience of the regulations covering animal experimentation, though training for the required certification (Home Office Personal Licence) will be provided
- experience of molecular science laboratory procedures
Shortlisted candidates for the ESR3 position will be required to complete the application process for the University of Glasgow.
The University of Glasgow requires the following additional documents at enrolment
- Final or current degree transcripts including grades (and an official translation, if needed) –scanned copy in colour of the original document
- Degree certificates (and an official translation, if needed): scanned copy in colour of the original document
- 2 references on headed paper (academic and/or professional).
- A certificate of English proficiency at the time of enrolment*
*English language proficiency certificate
For applicants whose first language is not English, the University sets a minimum English language proficiency level. A certificate of English proficiency at the time of enrolment is required such as IELTS (Academic) overall score 6.5 with no sub-test less than 6.0 and alternatives are listed at https://www.gla.ac.uk/international/englishlanguage/requirements. In certain circumstances a previous degree from an English speaking university may be accepted.
Proof of evidence for degree titles
- Foreign academic degrees and diplomas should be validated and recognized by the authorized personnel of the University of Glasgow before enrolment in the PhD programme
Salary and other benefits for the ESR enrolled at the University of Glasgow are according to EU-standards for Marie Skłodowska-Curie Actions and national regulations. The living allowance will be €3741 per month (gross amount-subject to employers costs, as well as employees tax and insurance) and appointed ESR will be eligible to pay local tax and insurance. Additional benefits are possible in the case of family allowances which will be €500 per month.
Each ESR will also have a Research and Training allowance which will be managed through the University of Glasgow. This will cover the participation of researchers in training activities;
- expenses related to research costs;
- tuition fees (where applicable).
- Visa, residency card for the recruited researcher and their family (where applicable)
A mobility allowance is also available. This will contribute to mobility related expenses of the ESR. The amount of the mobility allowance is specified in Table 1 of the MSCA Work Programme and for calls 2018-2020 and will amount to €600 per month.
Please refer to the general required documentation at https://www.gla.ac.uk/research/opportunities/howtoapplyforaresearchdegree/
The deadline for application is 21st May 2018 through the completion of the form under the section ‘send your application‘.